Targeted deletion in the β20–β21 loop of HIV envelope glycoprotein gp120 exposes the CD4 binding site for antibody binding
Author:
Publisher
Elsevier BV
Subject
Virology
Reference52 articles.
1. Biochemical and biological characterization of a dodecameric CD4-Ig fusion protein. Implications for therapeutic and vaccine strategies;Arthos;J. Biol. Chem.,2002
2. Human neutralizing monoclonal antibodies of the IgG1subtype protect against mucosal simian-human immunodeficiency virus infection;Baba;Nat. Med.,2000
3. HIV-1 inactivation by antibodies: predominance of a group-specific epitope that persists despite genetic variation;Berkower;J. Exp. Med.,1989
4. A predominant group-specific neutralizing epitope of HIV-1 maps to residues 342–511 of the envelope glycoprotein gp120;Berkower;J. Virol.,1991
5. Assembly, structure, and antigenic properties of virus-like particles rich in HIV-1 envelope gp120;Berkower;Virology,2004
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2. Enhanced expression of HIV and SIV vaccine antigens in the structural gene region of live attenuated rubella viral vectors and their incorporation into virions;Vaccine;2013-04
3. Structural Plasticity and Conformational Transitions of HIV Envelope Glycoprotein gp120;PLoS ONE;2012-12-27
4. Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04;Journal of Virology;2012-12-12
5. Spontaneous Rearrangement of the β20/β21 Strands in Simulations of Unliganded HIV-1 Glycoprotein, gp120;Biochemistry;2012-09-21
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