Binding of two zinc ions promotes liquid-liquid phase separation of Tau

Author:

Yatoui Dahbia,Tsvetkov Philipp O.,La Rocca Romain,Baksheeva Viktoriia E.,Allegro Diane,Breuzard Gilles,Ferracci Géraldine,Byrne Deborah,Devred François

Funder

Conseil Régional Provence-Alpes-Côte d'Azur

Ministère de l'Enseignement Supérieur et de la Recherche Scientifique

Centre National de la Recherche Scientifique

Aix-Marseille Université

Institut National de la Santé et de la Recherche Médicale

European Regional Development Fund

Publisher

Elsevier BV

Subject

Molecular Biology,General Medicine,Biochemistry,Structural Biology

Reference24 articles.

1. Role of tau as a microtubule-associated protein: structural and functional aspects;Barbier;Front. Aging Neurosci.,2019

2. Liquid–liquid phase separation of tau protein: the crucial role of electrostatic interactions;Boyko;J. Biol. Chem.,2019

3. Zinc induces depletion and aggregation of endogenous TDP-43;Caragounis;Free Radic. Biol. Med.,2010

4. Unraveling the mechanism of tau protein aggregation in presence of zinc ion: the earliest step of tau aggregation;Chowdhury,2022

5. The FUS protein: physiological functions and a role in amyotrophic lateral sclerosis;Efimova;Mol. Biol.,2017

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Zinc utilization by microglia in Alzheimer’s disease;Journal of Biological Chemistry;2024-05

2. Exploring the Influence of Zinc Ions on the Conformational Stability and Activity of Protein Disulfide Isomerase;International Journal of Molecular Sciences;2024-02-08

3. Liquid–liquid phase separation in Alzheimer’s disease;Journal of Molecular Medicine;2024-01-02

4. Modulation of biomolecular phase behavior by metal ions;Biochimica et Biophysica Acta (BBA) - Molecular Cell Research;2023-12

5. Application of biomarker-derived fluorescent probes for the detection of Alzheimer's disease;TrAC Trends in Analytical Chemistry;2023-12

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3