Electrochemical hydrodefluorination of an aromatic trifluoromethyl group with ammonia as the hydrogen source
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Reference50 articles.
1. Substitution Effect of the Trifluoromethyl Group on the Bioactivity in Medicinal Chemistry: Statistical Analysis and Energy Calculations
2. FDA-Approved Trifluoromethyl Group-Containing Drugs: A Review of 20 Years
3. Contribution of Organofluorine Compounds to Pharmaceuticals
4. Multiple Pathways for the Irreversible Inhibition of Steroid Sulfatase with Quinone Methide-Generating Suicide Inhibitors
5. Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate (S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385)
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