LP-16: Combining in vitro data and physiologically based kinetic modeling to predict liver toxicity of pyrrolizidine alkaloid rinderine in humans
Author:
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference6 articles.
1. Monocrotaline-induced liver toxicity in rat predicted by a combined in vitro physiologically based kinetic modeling approach;Suparmi;Arch Toxicol,2020
2. Combining In Vitro Data and Physiologically Based Kinetic Modeling Facilitates Reverse Dosimetry to Define In Vivo Dose–Response Curves for Bixin- and Crocetin-Induced Activation of PPARγ in Humans;Suparmi;Mol. Nutr. Food Res.,2020
3. PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat;Lehmann;Arch. Toxicol.,2023
4. Physiologically-Based Kinetic Modeling Predicts Similar In Vivo Relative Potency of Senecionine N-Oxide for Rat and Human at Realistic Low Exposure Levels;Widjaja;Mol. Nutr. Food Res.,2023
5. First record of pyrrolizidine alkaloids in the southern African biotype of Chromolaena odorata (Asteraceae);Dube;South African J. Bot.,2021
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