Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri

Author:

Zyserman Ingrid,Mondal Deboprosad,Sarabia Francisco,McKerrow James H.,Roush William R.,Debnath Anjan

Funder

National Institutes of Health

UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences

MINECO

Publisher

Elsevier BV

Subject

Immunology,General Medicine,Parasitology,Infectious Diseases

Reference24 articles.

1. Naegleria fowleri: characterization of a secreted histolytic cysteine protease;Aldape;Exp. Parasitol.,1994

2. Larrea tridentata: a novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri;Bashyal;PLoS Neglected Trop. Dis.,2017

3. Diagnosis, clinical course, and treatment of primary amoebic meningoencephalitis in the United States, 1937-2013;Capewell;J. Pediatr. Infect. Dis. Soc.,2015

4. Notes from the field: primary amebic meningoencephalitis associated with ritual nasal rinsing–St. Thomas, U.S. Virgin Islands, 2012;Centers for Disease, C., and Prevention;MMWR Morb. Mortal. Wkly. Rep.,2013

5. Investigational drug available directly from CDC for the treatment of infections with free-living amebae;Centers for Disease, C., and Prevention;MMWR Morb. Mortal. Wkly. Rep.,2013

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