Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia

Author:

Evans William E.,Horner Michelle,Chu Ya Qin,Kalwinsky David,Roberts W. Mark

Publisher

Elsevier BV

Subject

Pediatrics, Perinatology and Child Health

Reference17 articles.

1. Are children with lymphoblastic leukaemia given enough 6-mercaptopurine?;Lennard;Lancet,1987

2. Combined modality therapy of acute lymphocytic leukemia;Simone;Cancer,1975

3. Nobel lecture in physiology and medicine: the purine path to chemotherapy;Elion;In Vitro Cell Dev Biol,1989

4. Biochemical parameters of mercaptopurine activity in patients with acute lymphoblastic leukemia;Zimm;Cancer Res,1986

5. Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia;Lennard;Lancet,1990

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