Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models-Reference-Cited by-同舟云学术

Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models

Published:2013-01 Issue:1 Volume:23 Page:121-128
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Corcoran Ryan B.,Cheng Katherine A.,Hata Aaron N.,Faber Anthony C.,Ebi Hiromichi,Coffee Erin M.,Greninger Patricia,Brown Ronald D.,Godfrey Jason T.,Cohoon Travis J.,Song Youngchul,Lifshits Eugene,Hung Kenneth E.,Shioda Toshi,Dias-Santagata Dora,Singh Anurag,Settleman Jeffrey,Benes Cyril H.,Mino-Kenudson Mari,Wong Kwok-Kin,Engelman Jeffrey A.

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference28 articles.

1. Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers;Adjei;J. Clin. Oncol.,2008

2. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1;Barbie;Nature,2009

3. Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic;Cragg;J. Clin. Invest.,2008

4. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers;Engelman;Nat. Med.,2008

5. Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition;Faber;Proc. Natl. Acad. Sci. USA,2009

Cited by 340 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel inKRAS-mutated colorectal cancer;2024-09-06

2. The safety and efficacy of binimetinib for lung cancer: a systematic review;BMC Pulmonary Medicine;2024-08-01

3. The next-generation KRAS inhibitors…What comes after sotorasib and adagrasib?;Lung Cancer;2024-08

4. Defining melanoma combination therapies that provide senolytic sensitivity in human melanoma cells;Frontiers in Cell and Developmental Biology;2024-06-14

5. Combinatorial strategies to target RAS-driven cancers;Nature Reviews Cancer;2024-04-16