Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2-Reference-Cited by-同舟云学术

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Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2

Published:2006-06 Issue:6 Volume:9 Page:445-457
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Yang Yu-An,Zhang Gen-Mu,Feigenbaum Lionel,Zhang Ying E.

Funder

National Institutes of Health

National Cancer Institute

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference68 articles.

1. Molecular viral oncology of hepatocellular carcinoma;Block;Oncogene,2003

2. The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization;Chacko;Nat. Struct. Biol.,2001

3. Suppression of transforming growth factor-β-induced apoptosis through a phosphatidylinositol 3-kinase/Akt-dependent pathway;Chen;Oncogene,1998

4. Roles of autocrine TGF-β receptor and Smad signaling in adipocyte differentiation;Choy;J. Cell Biol.,2000

5. Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β induced apoptosis;Conery;Nat. Cell Biol.,2004

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1. Hepatitis B virus X protein and TGF-β: partners in the carcinogenic journey of hepatocellular carcinoma;Frontiers in Oncology;2024-06-19

2. The Role of TGF-β/SMAD Signaling in Hepatocellular Carcinoma: from Mechanism to Therapy and Prognosis;International Journal of Biological Sciences;2024

3. Development and evaluation of a risk score model based on a WNT score gene-associated signature for predicting the clinical outcome and the tumour microenvironment of hepatocellular carcinoma;International Journal of Immunopathology and Pharmacology;2023-12

4. Strategic Replication of the Hepatic Zonation In Vitro Employing a Biomimetic Approach;ACS Applied Bio Materials;2023-11-28

5. TGF-β1 contributes to the hepatic inflammation in animal models with nonalcoholic steatohepatitis by Smad3/TLR2 signaling pathway;Molecular Immunology;2022-12

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