JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer-Reference-Cited by-同舟云学术

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JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer

Published:2012-12 Issue:6 Volume:22 Page:796-811
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Britschgi Adrian,Andraos Rita,Brinkhaus Heike,Klebba Ina,Romanet Vincent,Müller Urs,Murakami Masato,Radimerski Thomas,Bentires-Alj Mohamed

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference57 articles.

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2. Potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor NVP-BSK805;Baffert;Mol. Cancer Ther.,2010

3. A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer;Berns;Cancer Cell,2007

4. Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury;Bertini;Proc. Natl. Acad. Sci. USA,2004

5. Putting tumours in context;Bissell;Nat. Rev. Cancer,2001

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