Structural Investigations of Human A2M Identify a Hollow Native Conformation That Underlies Its Distinctive Protease-Trapping Mechanism
Author:
Funder
Lundbeckfonden
Danish Council for Independent Research
Velux Fonden
Novo Nordisk Fonden
Publisher
Elsevier BV
Subject
Molecular Biology,Biochemistry,Analytical Chemistry
Reference70 articles.
1. A redetermination of the concentration of alpha 2-macroglobulin in human plasma;Coan;Biol. Chem. Hoppe Seyler,1989
2. The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism;Barrett;Biochem. J.,1973
3. The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins;Sottrup-Jensen;J. Biol. Chem.,1989
4. Architecture of native human alpha 2-macroglobulin studied by cryoelectron microscopy and three-dimensional reconstruction;Larquet;J. Struct. Biol.,1994
5. Ultrastructure of alpha 2-macroglobulins;Delain;Electron Microsc. Rev.,1992
Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Validation of electron-microscopy maps using solution small-angle X-ray scattering;Acta Crystallographica Section D Structural Biology;2024-06-27
2. Proteolytic cleavage of the TGFβ co‐receptor CD109 changes its conformation, resulting in protease inhibition via activation of its thiol ester, and dissociation from the cell membrane;The FEBS Journal;2024-04-08
3. Engineering New Protease Inhibitors Using α2-Macroglobulin;Methods in Molecular Biology;2023-12-02
4. Periostin C-Terminal Is Intrinsically Disordered and Interacts with 143 Proteins in an In Vitro Epidermal Model of Atopic Dermatitis;Biochemistry;2023-09-13
5. Alpha-2-macroglobulin prevents platelet aggregation induced by brain-derived neurotrophic factor;Biochemical Pharmacology;2023-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3