Phase 1b/2 Randomized Study of MEDI-575 in Combination With Carboplatin Plus Paclitaxel Versus Carboplatin Plus Paclitaxel Alone in Adult Patients With Previously Untreated Advanced Non–Small-Cell Lung Cancer-Reference-Cited by-同舟云学术

Phase 1b/2 Randomized Study of MEDI-575 in Combination With Carboplatin Plus Paclitaxel Versus Carboplatin Plus Paclitaxel Alone in Adult Patients With Previously Untreated Advanced Non–Small-Cell Lung Cancer

Published:2019-05 Issue:3 Volume:20 Page:e362-e368
ISSN:1525-7304
Container-title:Clinical Lung Cancer
language:en
Short-container-title:Clinical Lung Cancer

Author:

Wheatley-Price Paul,Gadgeel Shirish,Takahashi Toshiaki,Li Xia,Dar Mohammed,Blumenschein George R.

Funder

AstraZeneca

Lilly

MSD K.K.

ONO Pharmaceutical Co

Pfizer Japan

Taiho Pharmaceutical

Takeda Pharmaceutical Co., Ltd.

Adaptimmune

Bayer

Bristol-Myers Squibb

Celgene

Exelixis, Genentech

GlaxoSmithKline

Immatics

Incyte, Kite, MacroGenics

Merck

Novartis

Xcovery

MedImmune

Publisher

Elsevier BV

Subject

Cancer Research,Pulmonary and Respiratory Medicine,Oncology

Reference10 articles.

1. Diagnostic challenges in non–small-cell lung cancer: an integrated medicine approach;Salgia;Future Oncol,2015

2. The PDGF family: four gene products form five dimeric isoforms;Fredriksson;Cytokine Growth Factor Rev,2004

3. Antagonism of platelet-derived growth factor receptor in non small cell lung cancer: rationale and investigations;Bauman;Clin Cancer Res,2007

4. Inhibition of PDGFR-alpha by MEDI-575 reduces tumor growth and stromal fibroblast content in a model of non–small cell lung cancer;Laing;Mol Pharmacol,2013

5. Inhibition of PDGFRα in tumor stroma with MEDI-575 enhances activity of carboplatin/paclitaxel and delays tumor regrowth in a NSCLC xenograft model [abstract 100];Steiner;Eur J Cancer Suppl,2010

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Nonspecificity fingerprints for clinical-stage antibodies in solution;Proceedings of the National Academy of Sciences;2023-12-18

2. Non-specificity fingerprints for clinical stage antibodies in solution;2023-02-14

3. Targeting the PDGF/PDGFR signaling pathway for cancer therapy: A review;International Journal of Biological Macromolecules;2022-03

4. The best regimens for chemo-naïve incurable non-squamous non- small cell lung cancer with a programmed death-ligand 1, tumor proportion score 1–49%: a network meta-analysis;Translational Lung Cancer Research;2021-08

5. The impacts of race and regimens on the efficacy and safety of paclitaxel and platinum combination treatment for patients with advanced non-small cell lung cancer;European Journal of Clinical Pharmacology;2021-03-29