SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN)

Author:

Hall Victoria Jane,Foulkes Sarah,Charlett Andre,Atti Ana,Monk Edward J M,Simmons Ruth,Wellington Edgar,Cole Michelle J,Saei Ayoub,Oguti Blanche,Munro Katie,Wallace Sarah,Kirwan Peter D,Shrotri Madhumita,Vusirikala Amoolya,Rokadiya Sakib,Kall Meaghan,Zambon Maria,Ramsay Mary,Brooks Tim,Brown Colin S,Chand Meera A,Hopkins Susan,Andrews N,Atti A,Aziz H,Brooks T,Brown CS,Camero D,Carr C,Chand MA,Charlett A,Crawford H,Cole M,Conneely J,D'Arcangelo S,Ellis J,Evans S,Foulkes S,Gillson N,Gopal R,Hall L,Hall VJ,Harrington P,Hopkins S,Hewson J,Hoschler K,Ironmonger D,Islam J,Kall M,Karagiannis I,Kay O,Khawam J,King E,Kirwan P,Kyffin R,Lackenby A,Lattimore M,Linley E,Lopez-Bernal J,Mabey L,McGregor R,Miah S,Monk EJM,Munro K,Naheed Z,Nissr A,O'Connell AM,Oguti B,Okafor H,Organ S,Osbourne J,Otter A,Patel M,Platt S,Pople D,Potts K,Ramsay M,Robotham J,Rokadiya S,Rowe C,Saei A,Sebbage G,Semper A,Shrotri M,Simmons R,Soriano A,Staves P,Taylor S,Taylor A,Tengbe A,Tonge S,Vusirikala A,Wallace S,Wellington E,Zambon M,Corrigan D,Sartaj M,Cromey L,Campbell S,Braithwaite K,Price L,Haahr L,Stewart S,Lacey ED,Partridge L,Stevens G,Ellis Y,Hodgson H,Norman C,Larru B,Mcwilliam S,Winchester S,Cieciwa P,Pai A,Loughrey C,Watt A,Adair F,Hawkins A,Grant A,Temple-Purcell R,Howard J,Slawson N,Subudhi C,Davies S,Bexley A,Penn R,Wong N,Boyd G,Rajgopal A,Arenas-Pinto A,Matthews R,Whileman A,Laugharne R,Ledger J,Barnes T,Jones C,Botes D,Chitalia N,Akhtar S,Harrison G,Horne S,Walker N,Agwuh K,Maxwell V,Graves J,Williams S,O'Kelly A,Ridley P,Cowley A,Johnstone H,Swift P,Democratis J,Meda M,Callens C,Beazer S,Hams S,Irvine V,Chandrasekaran B,Forsyth C,Radmore J,Thomas C,Brown K,Roberts S,Burns P,Gajee K,Byrne TM,Sanderson F,Knight S,Macnaughton E,Burton BJL,Smith H,Chaudhuri R,Hollinshead K,Shorten RJ,Swan A,Shorten RJ,Favager C,Murira J,Baillon S,Hamer S,Gantert K,Russell J,Brennan D,Dave A,Chawla A,Westell F,Adeboyeku D,Papineni P,Pegg C,Williams M,Ahmad S,Ingram S,Gabriel C,Pagget K,Cieciwa P,Maloney G,Ashcroft J,Del Rosario I,Crosby-Nwaobi R,Reeks C,Fowler S,Prentice L,Spears M,McKerron G,McLelland-Brooks K,Anderson J,Donaldson S,Templeton K,Coke L,Elumogo N,Elliott J,Padgett D,Mirfenderesky M,Cross A,Price J,Joyce S,Sinanovic I,Howard M,Lewis T,Cowling P,Potoczna D,Brand S,Sheridan L,Wadams B,Lloyd A,Mouland J,Giles J,Pottinger G,Coles H,Joseph M,Lee M,Orr S,Chenoweth H,Auckland C,Lear R,Mahungu T,Rodger A,Penny-Thomas K,Pai S,Zamikula J,Smith E,Stone S,Boldock E,Howcroft D,Thompson C,Aga M,Domingos P,Gormley S,Kerrison C,Marsh L,Tazzyman S,Allsop L,Ambalkar S,Beekes M,Jose S,Tomlinson J,Jones A,Price C,Pepperell J,Schultz M,Day J,Boulos A,Defever E,McCracken D,Brown K,Gray K,Houston A,Planche T,Pritchard Jones R,Wycherley Diane,Bennett S,Marrs J,Nimako K,Stewart B,Kalakonda N,Khanduri S,Ashby A,Holden M,Mahabir N,Harwood J,Payne B,Court K,Staines N,Longfellow R,Green ME,Hughes LE,Halkes M,Mercer P,Roebuck A,Wilson-Davies E,Gallego L,Lazarus R,Aldridge N,Berry L,Game F,Reynolds T,Holmes C,Wiselka M,Higham A,Booth M,Duff C,Alderton J,Jory H,Virgilio E,Chin T,Qazzafi MZ,Moody AM,Tilley R,Donaghy T,Shipman K,Sierra R,Jones N,Mills G,Harvey D,Huang YWJ,Birch J,Robinson L,Board S,Broadley A,Laven C,Todd N,Eyre DW,Jeffery K,Dunachie S,Duncan C,Klenerman P,Turtle L,De Silva T,Baxendale H,Heeney JL

Funder

Public Health England

NIHR

United Kingdom Department of Health and Social Care

Publisher

Elsevier BV

Subject

General Medicine

Reference41 articles.

1. What reinfections mean for COVID-19;Iwasaki;Lancet Infect Dis,2020

2. Evidence of SARS-CoV-2 re-infection with a different genotype;Colson;J Infect,2020

3. Symptomatic SARS-CoV-2 re-infection of a health care worker in a Belgian nosocomial outbreak despite primary neutralizing antibody response;Selhorst;medRxiv,2020

4. Genomic evidence for reinfection with SARS-CoV-2: a case study;Tillett;Lancet Infect Dis,2021

5. Assessment of the risk of SARS-CoV-2 reinfection in an intense re-exposure setting;Abu-Raddad;medRxiv,2020

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