Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivo

Author:

Millan M.J,Dekeyne A,Gobert A

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Pharmacology

Reference10 articles.

1. Novel agonists of 5-HT2C receptors. Synthesis and biological evaluation of substitued 2-(indol-1-yl)-1-methylethylamines and 2-(indenol[1,2-b]pyrrol-1-methylethylamines. Improved therapeutics for obsessive compulsive disorder;Bös;J. Med. Chem.,1997

2. Serotoninergic modulation of midbrain dopamine systems;Kelland,1996

3. SB-242084, a selective and brain penetrant 5-HT2C receptor antagonist;Kennett;Neuropharmacology,1997

4. Dopamine, the prefrontal cortex and schizophrenia;Knable;J. Psychopharmacol.,1997

5. S 15535, a novel benzodioxopiperazine ligand of serotonin (5- HT)1A receptors: I. Interaction with cloned human (h)5-HT1A, dopamine hD2/hD3 and h2A-adrenergic receptors in relation to modulation of cortical monoamine release and potential antidepressant properties;Millan;J. Pharmacol. Exp. Ther.,1997

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