Management of sotorasib-related adverse events and hepatotoxicities following anti-PD-(L)1 therapy: Experience with sotorasib in two French anti-cancer centers and practical guidance proposal

Author:

Chour AliORCID,Basse ClémenceORCID,Lebossé Fanny,Bonte Pierre-Emmanuel,Girard Nicolas,Duruisseaux MichaëlORCID

Publisher

Elsevier BV

Reference21 articles.

1. Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial;de Langen;Lancet,2023

2. Severe Immune Checkpoint Inhibitor Hepatitis in KRAS G12C-Mutant NSCLC Potentially Triggered by Sotorasib: Case Report;Begum;JTO Clin. Res. Rep.,2021

3. A Rare Event of Liver Dysfunction on Sotorasib and Management Strategy;Kinahan;J. Adv. Pract. Oncol.,2022

4. Severe sotorasib-related hepatotoxicity and non-liver adverse events associated with sequential anti-PD(L)1 and sotorasib therapy in KRASG12C-mutant lung cancer;Chour;J. Thorac. Oncol.,2023

5. Clinical and Genomic Features of Response and Toxicity to Sotorasib in a Real-World Cohort of Patients With Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer;Thummalapalli;JCO Precis. Oncol.,2023

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