Adding first-line PD-1 inhibition to anti-VEGF and XELOX in pMMR metastatic colorectal cancer: Steppingstones, stumbling blocks, and next phase

Author:

Veen Torhild,Søreide KjetilORCID

Funder

Helse Vest Regionalt Helseføretak

Publisher

Elsevier BV

Reference10 articles.

1. First-line serplulimab in metastatic colorectal cancer: phase 2 results of a randomized, double-blind phase 2/3 trial;Wang;Med,2024

2. Neoadjuvant immunotherapy in primary and metastatic colorectal cancer;Kanani;Br. J. Surg.,2021

3. Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer;Veen;Cancer Immunol. Immunother.,2023

4. Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer;Chalabi;N. Engl. J. Med.,2024

5. Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers;Chalabi;Nat. Med.,2020

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