Asymmetric synthesis and preliminary evaluation of (R)- and (S)-[11C]bisoprolol, a putative β1-selective adrenoceptor radioligand

Author:

Soloviev Dmitri V.,Matarrese Mario,Moresco Rosa Maria,Todde Sergio,Bonasera Thomas A.,Sudati Francesco,Simonelli Pasquale,Magni Fulvio,Colombo Diego,Carpinelli Assunta,Galli Kienle Marzia,Fazio Ferruccio

Publisher

Elsevier BV

Subject

Cell Biology,Cellular and Molecular Neuroscience

Reference42 articles.

1. Synthesis of the [11C]labelled β-adrenergic receptor ligands atenolol, metoprolol and propranolol;Antoni;Appl. Radiat. Isot.,1989

2. Preparation and in vivo binding of [11C]carazolol, a radiotracer for the β-adrenergic receptor;Berridge;Int. J. Rad. Appl. Instrum. [B],1992

3. Specific non-β-adrenergic binding sites for 125I-iodocyanopindolol in myocardial membrane preparations: a comparative study between human, rat, and porcine hearts;Bjárnerheim;Cardiovasc. Res.,1991

4. Pharmacokinetics and metabolism of bisoprolol-14C in three animal species and in humans;Bohring;J. Cardiovasc. Pharmacol.,1986

5. Species differences in the localization and number of CNS β-adrenergic receptors: rat versus guinea pig;Booze;J. Pharm. Exp. Ther.,1989

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