Synthesis and antiproliferative activity of a series of novel 6-substituted pyrido[3,2- d ]pyrimidines as potential nonclassical lipophilic antifolates targeting dihydrofolate reductase-Reference-Cited by-同舟云学术

Synthesis and antiproliferative activity of a series of novel 6-substituted pyrido[3,2- d ]pyrimidines as potential nonclassical lipophilic antifolates targeting dihydrofolate reductase

Published:2017-03 Issue: Volume:128 Page:88-97
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Wang Meng,Yang Jiajia,Yuan Mengmeng,Xue Liangmin,Li Hao,Tian Chao,Wang Xiaowei,Liu Junyi,Zhang Zhili

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference32 articles.

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5. Identifying antimalarial compounds targeting dihydrofolate reductase-thymidylate synthase (DHFR-TS) by chemogenomic profiling;Aroonsri;Int. J. Parasitol.,2016

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