Synthesis of furanotriterpenoids from betulin and evaluation of Tyrosyl-DNA phosphodiesterase 1 (Tdp1) inhibitory properties of new semi-synthetic triterpenoids-Reference-Cited by-同舟云学术

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Synthesis of furanotriterpenoids from betulin and evaluation of Tyrosyl-DNA phosphodiesterase 1 (Tdp1) inhibitory properties of new semi-synthetic triterpenoids

Published:2024-10 Issue: Volume:276 Page:116724
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Tolmacheva Irina,Eroshenko Daria,Chernyshova Irina,Nazarov Mikhail,Lavrik Olga,Grishko Victoria

Funder

Ministry of Education and Science of the Russian Federation

Publisher

Elsevier BV

Reference37 articles.

1. Topoisomerase I inhibitors: challenges, progress and the road ahead;Talukdar;Eur. J. Med. Chem.,2022

2. Cellular roles of DNA topoisomerases: a molecular perspective;Wang;Nat. Rev. Mol. Cell Biol.,2002

3. Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages;Interthal;J. Biol. Chem.,2005

4. Natural products and their derivatives as inhibitors of the DNA repair enzyme tyrosyl-DNA phosphodiesterase 1;Zakharenko;Int. J. Mol. Sci.,2023

5. Usnic acid conjugates with monoterpenoids as potent tyrosyl-DNA phosphodiesterase 1 inhibitors;Luzina;J. Nat. Prod.,2020

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