Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide-Reference-Cited by-同舟云学术

Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide

Published:2009-09 Issue:9 Volume:44 Page:3433-3438
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Feng Wei,Satyanarayana Mavurapu,Tsai Yuan-Chin,Liu Angela A.,Liu Leroy F.,LaVoie Edmond J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference31 articles.

1. Tumor Cell Death Induced by Topoisomerase-Targeting Drugs

2. Topoisomerase Enzymes as Therapeutic Targets for Cancer Chemotherapy

3. Next generation topoisomerase I inhibitors: Rationale and biomarker strategies

4. Topoisomerase I inhibitors: camptothecins and beyond

5. Targeting topoisomerase I: molecular mechanisms and cellular determinants of response to topoisomerase I inhibitors

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