Human constitutive androstane receptor agonist DL5016: A novel sensitizer for cyclophosphamide-based chemotherapies

Author:

Liang Dongdong,Li Linhao,Lynch Caitlin,Mackowiak Bryan,Hedrich William D.,Ai Yong,Yin Yue,Heyward Scott,Xia Menghang,Wang Hongbing,Xue FengtianORCID

Funder

National Institute of General Medicine

Intramural Research Program of the National Center for Advancing Translational Sciences

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference41 articles.

1. An overview of cyclophosphamide development and clinical applications;Colvin;Curr. Pharmaceut. Des.,1999

2. The constitutive androstane receptor is a novel therapeutic target facilitating cyclophosphamide-based treatment of hematopoietic malignancies;Wang;Blood,2013

3. Metabolism of oxazaphosphorines;Sladek;Pharmacol. Ther.,1988

4. The chemistry of the metabolites of cyclophosphamide;Ludeman;Curr. Pharmaceut. Des.,1999

5. Human kidney tubules detoxify chloroacetaldehyde, a presumed nephrotoxic metabolite of ifosfamide;Dubourg;J. Am. Soc. Nephrol.,2001

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