A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study-Reference-Cited by-同舟云学术

A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study

Published:2016-05 Issue: Volume:113 Page:228-245
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Karki Radha,Jun Kyu-Yeon,Kadayat Tara Man,Shin Somin,Thapa Magar Til Bahadur,Bist Ganesh,Shrestha Aarajana,Na Younghwa,Kwon Youngjoo,Lee Eung-Seok

Funder

National Research Foundation of Korea

Ministry of Education, Science and Technology

Korean Health Technology R&D

Ministry of Health & Welfare

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference34 articles.

1. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines

2. Synthesis, antitumor activity, and structure–activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors

3. Resveratrol as a Chemopreventive Agent: A Promising Molecule for Fighting Cancer

4. Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo

5. Bioflavonoids as Poisons of Human Topoisomerase IIα and IIβ

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