Recent research results have converted gp120 binders to a therapeutic option for the treatment of HIV-1 infection. A medicinal chemistry point of view-Reference-Cited by-同舟云学术

Recent research results have converted gp120 binders to a therapeutic option for the treatment of HIV-1 infection. A medicinal chemistry point of view

Published:2022-02 Issue: Volume:229 Page:114078
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Governa Paolo,Manetti Fabrizio^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference82 articles.

1. Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation;Jette;Nat. Commun.,2021

2. The HIV-1 Env gp120 inner domain shapes the Phe43 cavity and the CD4 binding site;Prevost;mBio,2020

3. HIV-1 envelope conformation, allostery, and dynamics;Bennett;Viruses,2021

4. The conformational states of the HIV-1 envelope glycoproteins;Wang;Trends Microbiol.,2020

5. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody;Kwong;Nature,1998

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