Novel approach to bis(indolyl)methanes: De novo synthesis of 1-hydroxyiminomethyl derivatives with anti-cancer properties

Author:

Grosso Carla,Cardoso Ana Lúcia,Lemos AméricoORCID,Varela João,Rodrigues Maria João,Custódio Luísa,Barreira Luísa,Pinho e Melo Teresa M.V.D.

Funder

FCT

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference64 articles.

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3. Intrinsic acute toxicity and hepatic enzyme inducing properties of the chemoprotectants indole-3-carbinol and 5,10-dihydroindeno 1,2-b indole in mice;Shertzer;Food Chem. Toxicol.,1991

4. J.J. Talley, K. Sprott, J.P. Pearson, G.T. Milne, W. Schairer, J.J. Yang, C. Kim, T. Barden, R. Lundigran, A. Mermerian, M.G. Currie, Indole compounds, WO 2008019357, 2008.

5. Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles;Wattenberg;Cancer Res.,1978

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