Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: Palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides

Author:

Hassan Abdalla E.A.,Abou-Elkhair Reham A.I.,Riordan James M.,Allan Paula W.,Parker William B.,Khare Rashmi,Waud William R.,Montgomery John A.,Secrist John A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference44 articles.

1. Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines;Sorscher;Gene Ther.,1994

2. In vivo gene therapy of cancer with E. Coli purine nucleoside phosphorylase;Parker;Hum. Gene Ther.,1997

3. Cell to cell Contact is not required for bystander cell killing by Escherichia coli purine nucleoside phosphorylase;Hughes;J. Biol. Chem.,1998

4. Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene;Hughes;Cancer Res.,1995

5. Gene therapy of cancer: activation of nucleoside prodrugs with E. Coli purine nucleoside phosphorylase;Secrist;Nucleosides Nucleotides,1999

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