One molecule two goals: A selective P-glycoprotein modulator increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells
Author:
Funder
MIUR
Associazione Italiana Ricerca sul cancro
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference46 articles.
1. The intestinal barrier: a fundamental role in health and disease;Vancamelbeke;Expet Rev. Gastroenterol. Hepatol.,2017
2. Gastrointestinal mucosal barrier function and diseases;Oshima;J. Gastroenterol.,2016
3. Tight junction structure, function, and assessment in the critically ill: a systematic review;Vermette;Intensive Care Med. Exp.,2018
4. ABC pumps and their role in active drug transport;Colabufo;Curr. Top. Med. Chem.,2009
5. Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition;Zhou;Xenobiotica,2008
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Visible Light‐Promoted Mono‐Bromination of Aniline Derivatives and Nitrogen‐Containing Heterocyclic Compounds via Electron Donor‐Acceptor Complex;Asian Journal of Organic Chemistry;2024-07-25
2. Development of novel N-aryl-2,4-bithiazole-2-amine-based CYP1B1 degraders for reversing drug resistance;European Journal of Medicinal Chemistry;2024-06
3. Harmaline to Human Mitochondrial Caseinolytic Serine Protease Activation for Pediatric Diffuse Intrinsic Pontine Glioma Treatment;Pharmaceuticals;2024-01-19
4. Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels;Molecules;2023-11-10
5. Tetrazole and oxadiazole derivatives as bioisosteres of tariquidar and elacridar: New potent P-gp modulators acting as MDR reversers;European Journal of Medicinal Chemistry;2023-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3