Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-ҡB activators for the treatment of ALS
Author:
Funder
Muscular Dystrophy Association
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Pharmacology,General Medicine
Reference40 articles.
1. Current hypotheses for the underlying biology of amyotrophic lateral sclerosis;D Rothstein;Ann. Neurol.,2009
2. Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis;Foran;Antioxidants Redox Signal.,2009
3. Mitochondrial dysfunction in amyotrophic lateral sclerosis - a valid pharmacological target?;Muyderman;Br. J. Pharmacol.,2014
4. The role of environmental toxins on ALS: a case-control study of occupational risk factors;Su;JAMA Neurol,2016
5. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions;Bruijn;Neuron,1997
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