Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells

Author:

Kwak Seung-Hwa,Shin Seungheon,Lee Ji-Hyun,Shim Jin-Kyoung,Kim Minjeong,Lee So-Deok,Lee Aram,Bae Jinsu,Park Jin-Hee,Abdelrahman Aliaa,Müller Christa E.,Cho Steve K.,Kang Seok-Gu,Bae Myung Ae,Yang Jung Yoon,Ko HyojinORCID,Goddard William A.,Kim Yong-Chul

Funder

Basic Science Research Program

National Research Foundation of Korea

Ministry of Science

ICT & Future Planning

GIST-Caltech Research Collaboration

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference67 articles.

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2. Purine and pyrimidines;Burnstock;Cell. Mol. Life Sci.,2007

3. Receptors for purines and pyrimidines;Ralevic;Pharmacol. Rev.,1998

4. International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits;Khakh;Pharmacol. Rev.,2001

5. Molecular physiology of P2X receptor;North;Physiol. Rev.,2002

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