Synthesis and biological evaluation of 5-aminoethyl benzophenanthridone derivatives as DNA topoisomerase IB inhibitors-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of 5-aminoethyl benzophenanthridone derivatives as DNA topoisomerase IB inhibitors

Published:2019-09 Issue: Volume:178 Page:81-92
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Tang Wen-Lin,Zhang Yu,Hu De-Xuan,Yang Hui,Yu Qian,Chen Jian-Wen,Agama Keli,Pommier Yves,An Lin-Kun^ORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangdong Provincial Key Laboratory of Construction Foundation

National Institutes of Health, Bethesda, Maryland, USA

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference37 articles.

1. DNA topoisomerases;Wang;Annu. Rev. Biochem.,1996

2. A model for the mechanism of human topoisomerase I;Stewart;Science,1998

3. DNA topoisomerases: structure, function, and mechanism;Champoux;Annu. Rev. Biochem.,2001

4. DNA topoisomerases and their poisoning by anticancer and antibacterial drugs;Pommier;Chem. Biol.,2010

5. Roles of eukaryotic topoisomerases in transcription, replication and genomic stability;Pommier;Nat. Rev. Mol. Cell Biol.,2016

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1. Insights on Antitumor Activity and Mechanism of Natural Benzophenanthridine Alkaloids;Molecules;2023-09-13

2. Electro-organic synthesis of C-5 sulfenylated amino uracils: Optimization and exploring topoisomerase-I based anti-cancer profile;Bioorganic Chemistry;2023-09

3. Synthesis and Biological Activities of 11‐ and 12‐Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl‐DNA Phosphodiesterase 1 Inhibitors;ChemMedChem;2023-03-17

4. Synthesis of 11-aminoalkoxy substituted benzophenanthridine derivatives as tyrosyl-DNA phosphodiesterase 1 inhibitors and their anticancer activity;Bioorganic Chemistry;2022-06

5. Topoisomerase I inhibitors: Challenges, progress and the road ahead;European Journal of Medicinal Chemistry;2022-06

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