A quantum chemical study of the reactivity of acetaminophen (paracetamol) toxic metabolite N-acetyl-p-benzoquinone imine with deoxyguanosine and glutathione
Author:
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference88 articles.
1. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression;Chandrasekharan;P. Natl. Acad. Sci. U. S. A.,2002
2. Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H2 synthases;Boutaud;P. Natl. Acad. Sci. U. S. A.,2002
3. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man;Hinz;FASEB J.,2008
4. Acetaminophen selectively suppresses peripheral prostaglandin E2 release and increases COX-2 gene expression in a clinical model of acute inflammation;Lee;Pain,2007
5. Analgesic efficacy and safety of paracetamol-codeine combinations versus paracetamol alone: a systematic review;de Craen;BMJ,1996
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