Synthesis and biological evaluation of two new radiolabelled estrogens: [125I](E)-3-methoxy-17α-iodovinylestra-1,3,5(10),6-tetraen-17β-ol and [125I](Z)-3-methoxy-17α-iodovinylestra-1,3,5(10),6-tetraen-17β-ol

Author:

Melo e Silva M.Cristina,Patrı́cio Luciana,Gano Lurdes,Sá e Melo M.Luı́sa,Inohae Eiko,Mataka Shuntaro,Thiemann Thies

Publisher

Elsevier BV

Subject

Radiation

Reference18 articles.

1. Synthesis, receptor binding and tissue distribution of (17α,20E)- and (17 α,20Z)-21-[125I]iodo-19-norpregna-1,3,5(10),20-tetr aene-3,17-diol;Ali;J. Med. Chem.,1988

2. Synthesis of A-ring fluorinated derivatives of (17α,20E/Z)-[125I] iodovinylestradiols: effect on receptor binding and receptor-mediated target tissue uptake;Ali;J. Med. Chem.,1993

3. Synthesis and structure-affinity of a series of 7α-undecylestradiol derivatives: a potential vector for therapy and imaging of estrogen-receptor-positive cancers;Da Silva;J. Med. Chem.,1990

4. Estrogen imaging with 17α-[123I]Iodovinyl-11β-methoxyestradiol (MIVE2)- Part I. Radiotracer preparation and characterization;Foulon;Nucl. Med. Biol.,1992

5. Radioiodinated ligands for the estrogen receptor: effect of 3-O-methylation on tissue distribution;Franke;J. Nucl. Med.,1984

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