Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference36 articles.
1. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
2. Mutation spectrum of copper-induced DNA damage.
3. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents
4. Deficiency of 8-hydroxyguanine dna endonuclease activity and accumulation of the 8-hydroxyguanine in mutator mutant (mutM) of Escherichia coli
5. MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis
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