Functional expression of insulin receptor substrate-1 is required for insulin-stimulated mitogenic signaling.
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference27 articles.
1. Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells
2. Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
3. The insulin-elicited 160 kDa phosphotyrosine protein in mouse adipocytes is an insulin receptor substrate 1: Identification by cloning
4. Cloning and increased expression of an insulin receptor substrate - 1-like gene in human hepatocellular carcinoma
5. Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase
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1. The AP-1 Complex Regulates Intracellular Localization of Insulin Receptor Substrate 1, Which Is Required for Insulin-Like Growth Factor I-Dependent Cell Proliferation;Molecular and Cellular Biology;2013-05-15
2. Heparanase Enhances the Insulin Receptor Signaling Pathway to Activate Extracellular Signal-regulated Kinase in Multiple Myeloma;Journal of Biological Chemistry;2012-11
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4. Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors;Development;2008-10-01
5. Involvement of insulin-like growth factor-insulin receptor signal pathway in the transgenic mouse model of medulloblastoma;Cancer Science;2008-02
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