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TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease

  • Published:2017-08 Issue:4 Volume:170 Page:649-663.e13
  • ISSN:0092-8674
  • Container-title:Cell
  • language:en
  • Short-container-title:Cell

Author:

Ulland Tyler K.,Song Wilbur M.,Huang Stanley Ching-Cheng,Ulrich Jason D.,Sergushichev Alexey,Beatty Wandy L.,Loboda Alexander A.,Zhou Yingyue,Cairns Nigel J.,Kambal Amal,Loginicheva Ekaterina,Gilfillan Susan,Cella Marina,Virgin Herbert W.,Unanue Emil R.,Wang Yaming,Artyomov Maxim N.,Holtzman David M.,Colonna Marco

Funder

NIH

Knight ADRC

Cure Alzheimer’s Fund

National Multiple Sclerosis Society

Government of Russian Federation

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference55 articles.

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2. Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors;Arase;Science,2002

3. Apolipoprotein E is a ligand for triggering receptor expressed on myeloid cells 2 (TREM2);Atagi;J. Biol. Chem.,2015

4. The triggering receptor expressed on myeloid cells 2 binds apolipoprotein E;Bailey;J. Biol. Chem.,2015

5. Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome;Cho;Autophagy,2014

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