Salmeterol undergoes enantioselective bronchopulmonary distribution with receptor localisation a likely determinant of duration of action

Author:

Jacobson Glenn A.,Raidal SharanneORCID,Robson Kate,Narkowicz Christian K.,Nichols David S.ORCID,Walters E. Haydn

Funder

Division of Pharmacy, School of Medicine, University of Tasmania

School of Animal and Veterinary Sciences, Charles Sturt University

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference18 articles.

1. The beta-adrenoceptor pharmacology of the enantiomers of salmeterol;Nials;Am. Rev. Respir. Dis.,1994

2. Development of new stereoisomeric drugs;FDA;Guidances (Drugs),1992

3. Long-acting beta2-agonists in asthma: enantioselective safety studies are needed;Jacobson;Drug Saf.,2018

4. Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma;Cheung;N. Engl. J. Med.,1992

5. Effects of S-salbutamol on human isolated bronchus;Templeton;Pulm. Pharmacol. Ther.,1998

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