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Related impurities in peptide medicines

Published:2014-12 Issue: Volume:101 Page:2-30
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

D’Hondt Matthias,Bracke Nathalie,Taevernier Lien,Gevaert Bert,Verbeke Frederick,Wynendaele Evelien,De Spiegeleer Bart

Funder

Institute for the Promotion of Innovation through Science and Technology in Flanders (IWT-Vlaanderen)

Ghent University

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference171 articles.

1. Synthetic therapeutic peptides: science and market;Vlieghe;Drug Discov. Today,2010

2. Phage display-derived peptides as therapeutic alternatives to antibodies;Ladner;Drug Discov. Today,2004

3. Discovering and improving novel peptide therapeutics;McGregor;Curr. Opin. Pharmacol.,2008

4. Combinatorial peptide library methods for immunobiology research;Liu;Exp. Hematol.,2003

5. Bioactive peptides from libraries;Falciani;Chem. Biol.,2005

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1. Aspects of complexity in quality and safety assessment of peptide therapeutics and peptide-related impurities. A regulatory perspective;Regulatory Toxicology and Pharmacology;2024-11

2. A comprehensive study on the identification and characterization of major degradation products of synthetic liraglutide using liquid chromatography‐high resolution mass spectrometry;Journal of Peptide Science;2024-08-20

3. Unified and Versatile Multiplex Platform for Expedited Method Development and Comprehensive Characterization of Therapeutic Peptides;Analytical Chemistry;2024-08-17

4. Large-scale purification of a deprotected macrocyclic peptide by supercritical fluid chromatography (SFC) integrated with liquid chromatography in discovery chemistry;Journal of Chromatography A;2024-08

5. Development and validation of stability-indicating assay method and identification of force degradation products of glucagon-like peptide-1 synthetic analog Exenatide using liquid chromatography coupled with Orbitrap mass spectrometer;European Journal of Mass Spectrometry;2024-07-26

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