LC-MS/MS method for determination of r-RGD-hirudin in human plasma and its application in pharmacokinetic study

Author:

Peng Ai,Xiao LiORCID,Yang Lin,Yi Xiaoqin,Xiang JinORCID

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Reference18 articles.

1. Pharmacology of recombinant hirudin;Nowak;Semin. Thromb. Hemost.,2002

2. Medical leech therapy in plastic reconstructive surgery;Houschyar;Wien Med. Wochenschr.,2015

3. Pharmacological activities and mechanisms of hirudin and its derivatives - a Review;Junren;Front. Pharmacol.,2021

4. Thrombin is a therapeutic target for non-small-cell lung cancer to inhibit vasculogenic mimicry formation;Zhao;Signal Transduct. Targeted Ther.,2020

5. The role of exosomal CDC6 in the hirudin-mediated suppression of the malignant phenotype of bladder cancer cells;Shen;Gene,2022

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