Methyleugenol hepatocellular cancer initiating effects in rat liver

Author:

Williams Gary M.,Iatropoulos Michael J.,Jeffrey Alan M.,Duan Jian-Dong

Publisher

Elsevier BV

Subject

Toxicology,General Medicine,Food Science

Reference56 articles.

1. 14-Week toxicity and cell proliferation of methyleugenol administered by gavage to F344 rats and B6C3F1 mice;Abdo;Food Chem. Toxicol.,2001

2. Analytics Historical Control Data, 2010. Anilytics Inc., Gaithersburg, MD, USA.

3. Preneoplastic lesions as end points in carcinogenicity testing. I. Hepatic preneoplasia;Bannasch;Carcinogenesis,1986

4. Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1′-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1′-hydroxysafrole in mouse liver;Boberg;Cancer Res.,1983

5. Cytotoxicity and genotoxicity of methyleugenol and related congeners – a mechanism of activation for methyleugenol;Burkey;Mutat. Res.,2000

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