Stereoselective synthesis of novel (R)- and (S)-5-azidomethyl-2-oxazolidinones from (S)-epichlorohydrin: a key precursor for the oxazolidinone class of antibacterial agents

Author:

Madhusudhan G.,Om Reddy G.,Rajesh T.,Ramanatham J.,Dubey P.K.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference32 articles.

1. Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 1. The B group

2. Brickner, S. J.; Hutchinson, D. K.; Barbachyn, M. R.; Garmon, S. A.; Grega, K. C.; Hendges, S. K.; Manninen, P. R.; Toops, D. S.; Ulanowicz, D. A.; Kilburn, J. O.; Glickman, S.; Zurenko, G. E.; Ford, C. In 35th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, September, 1995, F 208, p 149.

3. Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

4. Antibacterials. Synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 4. Multiply-substituted aryl derivatives

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