An organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference29 articles.
1. Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase
2. Treatment of primary moderate hypercholesterolemia with lovastatin (mevinolin) and colestipol
3. The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis
4. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. I. Structural modification of 5-substituted 3,5-dihydroxypentanoic acids and their lactone derivatives
5. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 3. 7-(3,5-Disubstituted-[1,1'-biphenyl]-2-yl)-3,5-dihydroxy-6-heptenoic acids and their lactone derivatives
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3. Concise Stereoselective Total Synthesis of (4R, 6R)-Lactone Moiety Analog of Mevinoline and Compactin;Synthetic Communications;2013-08-08
4. Proline Catalyzed α-Aminoxylation Reaction in the Synthesis of Biologically Active Compounds;Accounts of Chemical Research;2012-11-13
5. Enzymatic Reductions for the Regio- and Stereoselective Synthesis of Hydroxy-keto Esters and Dihydroxy Esters;Organic Letters;2012-03-12
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