Segment coupling to a highly hindered N-terminal, alamethicin-related α-aminoisobutyric acid (Aib) residue

Author:

Carpino Louis A.,Abdel-Maksoud Adel Ali,Mansour E.M.E.,Zewail Mohamed A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference18 articles.

1. Mechanistic studies of peptide oxazolone racemization

2. 1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive

3. Effect of Tertiary Bases on O-Benzotriazolyluronium Salt-Induced Peptide Segment Coupling

4. Efficiency in Peptide Coupling: 1-Hydroxy-7-azabenzotriazole vs 3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine

5. For a recent review on the synthesis of peptides containing α,α-dialkyl amino acid including those incorporating these amino acids in consecutive positions see: Formaggio, F.; Broxterman, Q. B.; Toniolo, C. In Houben-Weyl, Methods in Organic Chemistry, Goodman, M.; Felix, A.; Moroder, L.; Toniolo, C., Eds.; Thieme: Stuttgart, Germany, 2003; Vol. E22c, pp 292–310.

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