Sofalcone, a gastroprotective drug, covalently binds to KEAP1 to activate Nrf2 resulting in anti-colitic activity
Author:
Funder
National Research Foundation of Korea
Ministry of Education
Publisher
Elsevier BV
Subject
Pharmacology
Reference36 articles.
1. Conventional drug therapy for inflammatory bowel disease;Bryant;Scand. J. Gastroenterol.,2015
2. Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents;Giudice;Methods Mol. Biol.,2010
3. Colon-targeted cell-permeable NFkappaB inhibitory peptide is orally active against experimental colitis;Hong;Mol. Pharm.,2012
4. What should be considered on design of a colon-specific prodrug?;Jung;Expert Opin. Drug Deliv.,2010
5. The effect of sofalcone on indomethacin-induced gastric ulcers in a Helicobacter pylori-infected gnotobiotic murine model;Kabir;Aliment. Pharmacol. Ther.,2000
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