In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations

Author:

Ferrari Federica,Cerlesi Maria Camilla,Malfacini Davide,Asth Laila,Gavioli Elaine C.,Journigan Blair V.,Kamakolanu Uma Gayathri,Meyer Michael E.,Yasuda Dennis,Polgar Willma E.,Rizzi Anna,Guerrini Remo,Ruzza Chiara,Zaveri Nurulain T.,Calo Girolamo

Funder

University of Ferrara (FAR grant to GC), CNPq, Brazil

National Institutes of Health, USA

Publisher

Elsevier BV

Subject

Pharmacology

Reference39 articles.

1. Relationship between binding affinity and functional activity of nociceptin/orphanin FQ;Adapa;Neuropeptides,1997

2. Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic-versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands;Asth;Neuropharmacology,2016

3. Lack of the nociceptin receptor does not affect acute or chronic nociception in mice;Bertorelli;Peptides,2002

4. Determination of activity for nociceptin in the mouse vas deferens;Berzetei-Gurske;Eur. J. Pharmacol.,1996

5. Medicinal chemistry, pharmacology, and biological actions of peptide ligands selective for the nociceptin/orphanin FQ receptor;Calo,2013

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