A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation-Reference-Cited by-同舟云学术

A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation

Published:2014-03 Issue:3 Volume:11 Page:459-468
ISSN:1547-5271
Container-title:Heart Rhythm
language:en
Short-container-title:Heart Rhythm

Author:

Bartos Daniel C.,Giudicessi John R.,Tester David J.,Ackerman Michael J.,Ohno Seiko,Horie Minoru,Gollob Michael H.,Burgess Don E.,Delisle Brian P.

Publisher

Elsevier BV

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference34 articles.

1. Congenital long QT syndrome;Crotti;Orphanet J Rare Dis,2008

2. K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current;Barhanin;Nature,1996

3. Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel;Sanguinetti;Nature,1996

4. Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias;Wang;Nat Genet,1996

5. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel;Marx;Science,2002

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4. Mutation location and IKs regulation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region;European Heart Journal;2021-09-10

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