Combinatorial treatment of brain samples from sheep with scrapie using sodium percarbonate, sodium dodecyl sulfate, and proteinase K increases survival time in inoculated susceptible sheep

Author:

Harm Tyler A.,Smith Jodi D.,Cassmann Eric D.,Greenlee Justin J.

Funder

Agricultural Research Service

U.S. Department of Agriculture

Oak Ridge Associated Universities

U.S. Department of Energy

Oak Ridge Institute for Science and Education

Publisher

Elsevier BV

Subject

General Veterinary

Reference46 articles.

1. New studies on the heat resistance of hamster-adapted scrapie agent: threshold survival after ashing at 600 degrees C suggests an inorganic template of replication;Brown;Proc. Natl. Acad. Sci. U. S. A.,2000

2. Association between incubation time and genotype in sheep experimentally inoculated with scrapie-positive brain homogenate;Bulgin;Am. 517 Vet. Res.,2006

3. Autoclave treatment of the classical scrapie agent US no. 13-7 and experimental inoculation to susceptible VRQ/ARQ sheep via the oral route results in decreased transmission efficiency;Cassmann;PLoS One,2020

4. Decontamination of prion protein (BSE301V) using a genetically engineered protease;Dickinson;J. Hosp. Infect,2009

5. Novel methods for disinfection of prion-contaminated medical devices;Fichet;Lancet,2004

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