Effects of PDE10A inhibitor MK-8189 in people with an acute episode of schizophrenia: A randomized proof-of-concept clinical trial

Author:

Mukai Yuki,Lupinacci Robert,Marder Stephen,Snow-adami Linda,Voss Tiffini,Smith Sean M.,Egan Michael F.

Publisher

Elsevier BV

Reference36 articles.

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2. Combination of the phosphodiesterase 10A inhibitor, MR1916 with risperidone shows additive antipsychotic-like effects without affecting cognitive enhancement and cataleptic effects in rats;Arakawa;Neuropsychopharmacol Rep,2020

3. Update on weight-gain caused by antipsychotics: a systematic review and meta-analysis;Barton;Expert Opin. Drug Saf.,2020

4. The clinical global impressions scale: applying a research tool in clinical practice;Busner;Psychiatry (Edgmont),2007

5. Discovery of [11C]MK-8193 as a PET tracer to measure target engagement of phosphodiesterase 10A (PDE10A) inhibitors;Cox;Bioorg. Med. Chem. Lett.,2015

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