Old class but new dimethoxy analogue of benzimidazole: a bacterial topoisomerase I inhibitor

Author:

Bansal Sandhya,Tawar Urmila,Singh Manish,Nikravesh Abbas,Good Liam,Tandon Vibha

Publisher

Elsevier BV

Subject

Pharmacology (medical),Infectious Diseases,Microbiology (medical),General Medicine

Reference13 articles.

1. Human DNA topoisomerase I: relaxation, roles, and damage control;Leppart;Chromosoma,2005

2. DNA topoisomerases;Wang;Annu Rev Biochem,1996

3. DNA topoisomerases: structure, function and mechanism;Champoux;Annu Rev Biochem,2001

4. Betulinic acid, a potent inhibitor of eukaryotic topoisomerase I: identification of the inhibitory step, the major functional group responsible and development of more potent derivatives;Chowdhury;Med Sci Monit,2002

5. An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3,3′-di-indolylmethane, a novel DNA topoisomerase I poison with a strong binding affinity to the enzyme;Roy;Biochem J,2008

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