Single Acetylation-mimetic Mutation in TDP-43 Nuclear Localization Signal Disrupts Importin α1/β Signaling-Reference-Cited by-同舟云学术

Single Acetylation-mimetic Mutation in TDP-43 Nuclear Localization Signal Disrupts Importin α1/β Signaling

Published:2024-10 Issue:20 Volume:436 Page:168751
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Ko Ying-Hui,Lokareddy Ravi K.^ORCID,Doll Steven G.^ORCID,Yeggoni Daniel P.,Girdhar Amandeep,Mawn Ian^ORCID,Klim Joseph R.^ORCID,Rizvi Noreen F.,Meyers Rachel,Gillilan Richard E.^ORCID,Guo Lin^ORCID,Cingolani Gino^ORCID

Funder

National Institute of Neurological Disorders and Stroke

National Institutes of Health Office of Research Infrastructure Programs

National Institutes of Health

National Science Foundation

Frederick National Laboratory for Cancer Research

Dr. Ralph and Marian Falk Medical Research Trust

National Institute of General Medical Sciences

National Cancer Institute

Empire State Development's Division of Science, Technology and Innovation

Naples Children and Education Foundation

Publisher

Elsevier BV

Reference80 articles.

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3. Importin alpha/beta and the tug of war to keep TDP-43 in solution: quo vadis?;Doll;Bioessays,2022

4. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis;Neumann;Science,2006

5. Amyotrophic lateral sclerosis: a clinical review;Masrori;Eur. J. Neurol.,2020

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1. Acetylation of lysine 82 initiates TDP-43 nuclear loss of function by disrupting its nuclear import;2024-09-07