Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States-Reference-Cited by-同舟云学术

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Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States

Published:2021-11 Issue:23 Volume:433 Page:167295
ISSN:0022-2836
Container-title:Journal of Molecular Biology
language:en
Short-container-title:Journal of Molecular Biology

Author:

Gollapudi Sampath K.,Ma Weikang,Chakravarthy Srinivas,Combs Ariana C.,Sa Na,Langer Stephen,Irving Thomas C.,Nag Suman

Funder

Office of Science

National Institutes of Health

Argonne National Laboratory

U.S. Department of Energy

University of Colorado Boulder

University of Massachusetts

University of California, San Francisco

National Institute of General Medical Sciences

MyoKardia

Publisher

Elsevier BV

Subject

Molecular Biology,Structural Biology

Reference71 articles.

1. Regulation of contraction in striated muscle;Gordon;Physiol. Rev.,2000

2. Calcium, thin filaments, and the integrative biology of cardiac contractility;Kobayashi;Physiology,2005

3. Atomic model of a myosin filament in the relaxed state;Woodhead;Nature,2005

4. Three-dimensional structure of vertebrate cardiac muscle myosin filaments;Zoghbi;Proc. Natl. Acad. Sci.,2008

5. Three-dimensional image reconstruction of dephosphorylated smooth muscle heavy meromyosin reveals asymmetry in the interaction between myosin heads and placement of subfragment 2;Wendt;Proc. Natl. Acad. Sci.,2001

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2. Reassessing the unifying hypothesis for hypercontractility caused by myosin mutations in hypertrophic cardiomyopathy;The EMBO Journal;2024-08-27

3. Mechanisms of a novel regulatory light chain–dependent cardiac myosin inhibitor;Journal of General Physiology;2024-07-31

4. Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy;Nature Cardiovascular Research;2024-07-23

5. MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy;Journal of Molecular and Cellular Cardiology;2024-06

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