Cytochrome 450 metabolites of arachidonic acid (20-HETE, 11,12-EET and 14,15-EET) promote pheochromocytoma cell growth and tumor associated angiogenesis

Author:

Colombero Cecilia,Cárdenas Sofía,Venara Marcela,Martin Ayelen,Pennisi Patricia,Barontini Marta,Nowicki Susana

Funder

National Cancer Institute

INC-Argentina

Argentinean National Research Council

Publisher

Elsevier BV

Subject

General Medicine,Biochemistry

Reference43 articles.

1. Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase;Capdevila;J. Lipid Res.,2000

2. Metabolism of arachidonic acid to 20-hydroxy-5,8,11, 14-eicosatetraenoic acid by P450 enzymes in human liver: involvement of CYP4F2 and CYP4A11;Powell;J. Pharmacol. Exp. Therapeut.,1998

3. 20-HETE-producing enzymes are up-regulated in human cancers;Alexanian;CANCER GENOMICS PROTEOMICS,2012

4. Cytochrome P450 ω-hydroxylases in inflammation and cancer;Johnson;Adv. Pharmacol.,2015

5. Pharmacology & Therapeutics Cytochrome P450 epoxygenases and cancer: a genetic and a molecular perspective;Sausville;Pharmacol. Ther.,2019

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