Joint deletion of multifunctional MGF505-7R and H240R genes generates a safe and effective African swine fever virus attenuated live vaccine candidate
Author:
Funder
National Natural Science Foundation of China
Publisher
Elsevier BV
Reference9 articles.
1. Deletion of African Swine Fever vVirus (ASFV) H240R gene attenuates the virulence of ASFV by enhancing NLRP3-mediated inflammatory responses;Huang;J. Virol.,2023
2. African swine fever virus MGF-505-7R negatively regulates cGAS-STING-mediated signaling pathway;Li;J. Immunol.,2021
3. African swine fever virus protein MGF-505-7R promotes virulence and pathogenesis by inhibiting JAK1- and JAK2-mediated signaling;Li;J. Biol. Chem.,2021
4. pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1beta and type I IFN production;Li;PLoS Pathog.,2021
5. Development of a new effective African swine fever virus vaccine candidate by deletion of the H240R and MGF505-7R genes results in protective immunity against the Eurasia strain;Li;J. Virol.,2023
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